浏览全部资源
扫码关注微信
南京师范大学 泰州学院,江苏 泰州 225300
[ "刘永安,副教授,博士,硕士生导师,江苏高校“青蓝工程”中青年学术带头人。主要研究方向:科技哲学和科技伦理。主持教育部项目2项、江苏省教育厅项目2项,参研国家社科基金和江苏省社科基金项目数项。出版学术专著1部,在《自然辩证法研究》《自然辩证法通讯》等学术期刊发表论文20余篇。Email:anyongliu2012@sina.com" ]
收稿日期:2024-11-08,
修回日期:2024-12-07,
纸质出版日期:2024-12-25
移动端阅览
刘永安.从机器隐喻到自组织范式:合成生物的本体论探赜[J].新兴科学和技术趋势,2024,3(4):353-360.
LIU Yong’an.From machine metaphor to self-organizing paradigm: exploring the ontology of synthetic organisms[J].Emerging Science and Technology,2024,3(4):353-360.
刘永安.从机器隐喻到自组织范式:合成生物的本体论探赜[J].新兴科学和技术趋势,2024,3(4):353-360. DOI: 10.12405/j.issn.2097-1486.2024.04.005.
LIU Yong’an.From machine metaphor to self-organizing paradigm: exploring the ontology of synthetic organisms[J].Emerging Science and Technology,2024,3(4):353-360. DOI: 10.12405/j.issn.2097-1486.2024.04.005.
机器隐喻对合成生物做出了一种机器本体论的设定,机器本体论既不能揭示合成生物学的技术本质也不能充分反映合成生物在本体论上的新颖性。作为“技术自然化”的先锋代表,合成生物学的技术本质体现在对生物自组织能力的利用。合成生物技术展现出技术与自然的融合趋向,其造物合成生物兼具人工(机器)和自然(生物)的双重本体特征,合成生物在本体论上应被概念化为一种更具包容性的混合本体。混合本体论不仅为反思机器本体论的局限性提供了一种批判性的视角,同时也使我们能在新的维度上对合成生物学未来的技术潜力形成新的认识。
The machine metaphor has set a machine ontology for synthetic organisms. However, the machine ontology can neither reveal the technical essence of synthetic biology nor fully reflect the ontological novelty of synthetic organisms. As a pioneer representative of “technology naturalized”, the technical essence of synthetic biology lies in its utilization of biological self-organizing capabilities. Synthetic biotechnology shows an integration of technology and nature. Its product, synthetic organisms, exhibits dual ontological characteristics, being both artificial (machine) and natural (biological). Ontologically, synthetic organisms should be conceptualized as a more inclusive hybrid ontology. This hybrid ontology not only provides a critical perspective of reflecting on the limitations of machine ontology, but also allows us to develop a new understanding of the future technological potential of synthetic biology from a novel dimension.
LUCZAJ M H , BLOK V . How to Deal with Hybrids in the Anthropocene? Towards a Philosophy of Technology and Environmental Philosophy 2.0 [J]. Environmental Values , 2019 , 28 ( 3 ): 325 - 345 . DOI: 10.3197/096327119X15519764179818 http://dx.doi.org/10.3197/096327119X15519764179818 .
NORDMANN A . Technology Naturalized: A Challenge to Design for the Human Scale [C]//PIETER E, VERMAAS,PETER K, et al. (Eds) Philosophy and Design : From Engineering to Architecture. Dordrecht: Springer , 2008 : 173 - 184 .
EUROPEAN COMMISSION . Synthetic biology: Applying engineering to biology (Report of a NEST High Level Expert Group) [R]. Brussels : European Commission , 2005 : 5 .
PÜHLER A , RÖBER B M , et al . Synthetische Biologie: Die Geburt einer neuen Technikwissenschaft [M]. Berlin/Heidelberg : Springer , 2011 : 6 .
CLARKE L , KITNEY R . Developing synthetic biology for industrial biotechnology applications [J]. Biochemical Society Transactions , 2020 , 48 ( 1 ): 113 - 122 . DOI: 10.1042/BST20190349 http://dx.doi.org/10.1042/BST20190349 .
BOLDT J . Machine metaphors and ethics in synthetic biology [J]. Life Sciences, Society and Policy , 2018 , 14 ( 1 ): 1 - 13 . DOI: 10.1186/s40504-018-0077-y http://dx.doi.org/10.1186/s40504-018-0077-y .
RIJSSENBEEK J , BLOK V , ROBAEY Z . Metabolism Instead of Machine: Towards an Ontology of Hybrids [J]. Philosophy & Technology , 2022 , 35 ( 3 ): 1 - 23 . DOI: 10.1007/s13347-022-00554-y http://dx.doi.org/10.1007/s13347-022-00554-y .
NIELSEN J , KEASLING J D . Engineering cellular metabolism [J]. Cell , 2016 , 164 ( 6 ): 1185 - 1197 . DOI: 1016/j.cell.2016.02.004 http://dx.doi.org/1016/j.cell.2016.02.004 .
KOGGE W , RICHTER M . Synthetic biology and its alternatives: Descartes, Kant and the idea of engineering biological machines [J]. Studies in History and Philosophy of Biological and Biomedical Sciences , 2013 , 44 ( 2 ): 181 - 189 . DOI: 10.1016/j.shpsc.2013.03.013 http://dx.doi.org/10.1016/j.shpsc.2013.03.013 .
XUEQIN L , GIL A H , XINYU B , et al . New synthetic biology tools for metabolic control [EB/OL].( 2022-04-27 )[ 2024-11-02 ]. https://pubmed.ncbi.nlm.nih.gov/35489308/.2022-4-27 https://pubmed.ncbi.nlm.nih.gov/35489308/.2022-4-27 .
费多益 . 目的论视角的生命科学解释模式反思 [J]. 中国社会科学 , 2019 ( 04 ): 142 - 159 .
SCHMIDT J C . Prospective Technology Assessment of Synthetic Biology: Fundamental and Propaedeutic Reflections in Order to Enable an Early Assessment [J]. Sci Eng Ethics , 2016 , 22 ( 4 ): 1151 - 1170 . DOI: 10.1007/s11948-015-9673-x http://dx.doi.org/10.1007/s11948-015-9673-x .
Pottage A , Sherman B . Organisms and manufactures: On the history of plant inventions [J]. Melbourne University Law Review , 2007 , 31 ( 2 ): 539 - 568 . DOI: 10.3316/agispt.20082978 http://dx.doi.org/10.3316/agispt.20082978 .
POLLACK J . Breaking the limits on design complexity [A]//Roco M C, Bainbridge W S. (Eds) Converging technologies for improving human performance[C] . Dordrecht : Springer , 2003 : 161 - 164 .
亚里士多德 . 灵魂论及其他 [M]. 吴寿彭,译,北京 : 商务印书馆 , 2009 .
康德 . 判断力批判 [M]. 邓晓芒,译,北京 : 人民出版社 , 2017 .
ZEMP A D . The moral impact of synthesising living organisms: Biocentric views on synthetic biology [J]. Environmental Values , 2012 , 21 ( 1 ): 63 - 82 . DOI: 10.3197/096327112X13225063228023 http://dx.doi.org/10.3197/096327112X13225063228023 .
SCHYFTER P . Technological biology? Things and kinds in synthetic biology [J]. Biology and Philosophy , 2012 , 27 ( 1 ): 29 - 48 . DOI: 10.1007/s10539-011-9288-9 http://dx.doi.org/10.1007/s10539-011-9288-9 .
TAYLOR P W . Respect for nature a theory of envronmental ethics [M]. Princeton : Princeton University Press , 1986 : 45 .
常晓宇 , 季蕾 , 黄玉杰 , 等 . 石油烃微生物降解基因及其工程菌应用研究进展 [J]. 中国环境科学 , 2023 , 43 ( 08 ): 4305 - 4315 . DOI: 10.19674/j.cnki.issn1000-6923.20230628.005 http://dx.doi.org/10.19674/j.cnki.issn1000-6923.20230628.005 .
MACOVEI O . Epistemological Approaches on Systemic and Synthetic Biology [J]. BRAIN. Broad Research in Artificial Intelligence and Neuroscience , 2022 , 13 ( 4 ): 471 - 495 . DOI: 10.18662/brain/13.4/400 http://dx.doi.org/10.18662/brain/13.4/400 .
MALLEY M A . Exploration, iterativity and kludging in synthetic biology [J]. Comptes Rendus Chimie , 2011 , 14 ( 4 ): 406 - 412 . DOI: 10.1016/j.crci.2010.06.021 http://dx.doi.org/10.1016/j.crci.2010.06.021 .
刘海龙 . 合成生物究竟是人工物还是自然物:从其概念的内在矛盾谈起 [J]. 自然辩证法研究 , 2022 , 38 ( 10 ): 50 - 55 . DOI: 10.19484/j.cnki.1000-8934.2022.10.015 http://dx.doi.org/10.19484/j.cnki.1000-8934.2022.10.015 .
NICHOLSON D J . Is the Cell Really a Machine? [J]. Journal of Theoretical Biology , 2019 , 477 ( 2 ): 108 - 126 . DOI: 10.1016/j.jtbi.2019.06.002 http://dx.doi.org/10.1016/j.jtbi.2019.06.002 .
LUCZAJ M H , Blok V . Hybrids and the Boundaries of Moral Considerability or Revisiting the Idea of Non-Instrumental Value [J]. Philosophy & Technology , 2021 , 34 ( 2 ): 223 - 242 . DOI: 10.1007/s13347-01-00380-9 http://dx.doi.org/10.1007/s13347-01-00380-9 .
陈国强 , 谭丹 . 重编程微生物底盘用于PHA材料的定制化低成本生物合成 [J]. 合成生物学 , 2024 , 5 ( 05 ): 1211 - 1226 . DOI: 10.12211/2096-8280.2024-024 http://dx.doi.org/10.12211/2096-8280.2024-024 .
曾庆璐 , 郝庭彬 . 微藻合成生物学应用及前景 [J]. 新兴科学和技术趋势 , 2024 , 3 ( 01 ): 52 - 61 . DOI: 10.12405/j.issn.2097-1486.2024.01.006 http://dx.doi.org/10.12405/j.issn.2097-1486.2024.01.006 .
朱华伟 , 李寅 . 生物光伏:环境友好的新型太阳能利用技术 [J]. 合成生物学 , 2023 , 4 ( 06 ): 1259 - 1280 . DOI: 10.12211/2096-8280.2023-039 http://dx.doi.org/10.12211/2096-8280.2023-039 .
0
浏览量
0
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构